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Dose titration Watchful dose titration is important Firstly of treatment with methylphenidate. Dose titration really should be started off at the lowest probable dose.哌甲酯及其主要代谢物利他林酸可在血浆、血清或全血中检验，以监测病人是否按医嘱用药，确认可能的中毒者，或协助剂量致命时的法医